Formulation and Evaluation of Orally Fast Dispersing Tablets of Terbutaline Sulphate
Abstract
Gupta Kulbhushan*, Arora Vandana, Bhalla Vijay
The present research work was undertaken to develop mouth dissolving tablet of terbutaline sulphate with benefits to the patients. Superdisintegrants such as Crospovidone, Crosscarmellose and Sodium Starch Glycolate were used. A combination of two different diluents in various concentrations was used along with superdisintegrants. The tablets were prepared by direct compression method. The tablets were evaluated for hardness, friability, weight variation, wetting time, disintegration time and the selected formulation was compared with in vitro dissolution test. It was concluded that a mixture of diluents improves disintegrate rapidly and provide rapid onset of action as compare with conventional formulation.
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