An Overview on: The Formulation of Nano Medicines Using Probe Sonication Method for Enhancement of Oral Bioavailability
Abstract
Lina Eltaib
This session will present concepts, methods, and techniques to develop Nano medicines for oral delivery. Many of the broad-spectrum antibiotic used to treat bacterial infections; however, its limited aqueous solubility inhibits its broader clinical uses.(1) One of the major problems associated with poorly soluble drugs is very low bioavailability. Nanosuspension offers the unique advantage of increasing solubility of the drug resulting into faster drug absorption and hence achieving faster maximum plasma concentration. The purpose is to use of probe sonicator for nanocrystals preparation. Stabilized of nanosuspension using different surfactants and polymer. Enhancement of solubility and oral bioavailability. This enhanced dissolution and bioavailability of nanocrystals could be the promising approach for oral delivery.
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