• Pharmacognostic and Antimicrobial Screening of Leaf Extracts of Annona muricata

      Background: Medicinal plants have continued to attract attention in the global search for effective antimicrobial agents that can combat resistant pathogens that have been rendering many conventional drugs obsolete in the treatment of infections. Aim: To determine the pharmacognostic and antimicrobial effect of the leaf of Annona muricata. Materials and methods: The pharmacognostic evaluation of the leaf of A.muricatawas carried out using microscopic, macroscopic, chemomicroscopic, and phytochemical methods; while the antimicrobial activity was determined using agar cup diffusion technique. Results: The Chemomicroscopic evaluation revealed the presence of lignin, starch, and cellulose. Phytochemical analysis revealed the presence of alkaloids, tannins, saponins and carbohydrates. The extract showed varied inhibitory effects against the test-microorganisms Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Aspergillusniger and Candida albicans at concentrations 10-100 g/ml. Conclusion: The results of this study demonstrated the antimicrobial potential of Annona muricata and the basis for its inclusion in herbal preparations used to treat infectious diseases. Download